Pdcd6ip^tm1.2Adz

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Species

Mus musculus

Symbol

Pdcd6ip^tm1.2Adz

Category

allele

Allele of gene

Pdcd6ip

Transgenic Constructs

None

Synonyms

• Alix^-

Description

One loxP site was inserted just upstream of exon 2 and a second loxP site 61 bp into exon 3. An FRT flanked neomycin resistance gene cassette was inserted into intron 1. Flp mediated recombination removed the neo cassette. The sequence representing exon 2 through most of exon 3 was deleted through cre-mediated recombination. Western blot analysis confirmed the absence of protein expression in brain, lung, liver, pancreas, and thymus lysates from homozygous mutant mice.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations