Allele/Variant

Pdcd6iptm1.2Adz

Species
Mus musculus
Symbol
Pdcd6iptm1.2Adz
Category
allele
Allele of gene
Pdcd6ip
Transgenic Constructs
None
Synonyms
  • Alix-
Description
One loxP site was inserted just upstream of exon 2 and a second loxP site 61 bp into exon 3. An FRT flanked neomycin resistance gene cassette was inserted into intron 1. Flp mediated recombination removed the neo cassette. The sequence representing exon 2 through most of exon 3 was deleted through cre-mediated recombination. Western blot analysis confirmed the absence of protein expression in brain, lung, liver, pancreas, and thymus lysates from homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations