Version: 8.0.0
Date: Tue Jan 28 2025
Pon3tm1Dmsh
MGI:5825222
Allele of Pon3
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Pon3tm1Dmsh

Species
Mus musculus
Symbol
Pon3tm1Dmsh
Category
allele
Allele of gene
Pon3
Transgenic Constructs
None
Synonyms
  • Pon3KO
Description
A neomycin resistance cassette replaced exon 4. Western blot analysis confirmed the absence of protein expression in the liver. Lovastatinase activity is absent in liver homogenates of homozygous mutant mice, indicating complete loss of enzymatic activity.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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