Allele/Variant

Muc4tm1Skb

Species
Mus musculus
Symbol
Muc4tm1Skb
Category
allele
Allele of gene
Muc4
Transgenic Constructs
None
Synonyms
None
Description
The insertion of the L1L2_Bact_P cassette created a deletion of size 9176 starting at position 32569030 and ending at position 32579762 of Chromosome 16 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon 2 through 6. The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. RT-PCR confirmed the absence of transcript expression in the colon and lungs.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
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