Allele/Variant

Slc44a2tm1.2Tec

Species
Mus musculus
Symbol
Slc44a2tm1.2Tec
Category
allele
Allele of gene
Slc44a2
Transgenic Constructs
None
Synonyms
  • Slc44a2delta
Description
A targeting vector containing an FRT-flanked PGK-Neo selection cassette followed by a loxP site inserted upstream of exon 3 and another loxP site was inserted downstream of exon 10. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 3 through 10 floxed. Germ line, cre mediated recombination removed exons 3-10, which contain the first and largest extracellular loop of the protein. Immunoprecipitation of lung and kidney tissues confirmed that no protein was expressed in mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations