Allele/Variant

Tgfbitm1.1Nap

Species
Mus musculus
Symbol
Tgfbitm1.1Nap
Category
allele
Allele of gene
Tgfbi
Transgenic Constructs
None
Synonyms
  • Bigh3-
Description
A loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 1. Cre-mediated recombination removed the selection cassette and exon 1. Western blotting and immunohistochemistry confirmed the absence of protein (even of a smaller size) in the cornea of homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations