Version: 8.0.0
Date: Tue Jan 28 2025
Plekhm1tm1.2Hzhao
MGI:5888869
Allele of Plekhm1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Plekhm1tm1.2Hzhao

Species
Mus musculus
Symbol
Plekhm1tm1.2Hzhao
Category
allele
Allele of gene
Plekhm1
Transgenic Constructs
None
Synonyms
  • Plekhm1-
Description
The targeting vector was designed to insert a loxP site upstream of exon 3 and an FRT-flanked neomycin resistance (neo) cassette, followed by a second loxP site, downstream of exon 3. Germline Flp- and Cre- mediated recombination removed the FRT-flanked neo cassette and exon 3 sequences. Quantitative real-time PCR analysis confirmed the absence of exon 3 genomic DNA in several soft tissues and tibial bone from homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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