Allele/Variant

Usp21tm1c(EUCOMM)Wtsi

Species
Mus musculus
Symbol
Usp21tm1c(EUCOMM)Wtsi
Category
allele
Allele of gene
Usp21
Transgenic Constructs
None
Synonyms
  • Usp21flox
  • Usp21Loxp
Description
The L1L2_Bact_P cassette was inserted at position 171111927 of Chromosome 1 upstream of exon 3 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 6 at position 171113776. Exons 3-6 are thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele to remove the lacZ sequence and neo selection cassette, leaving loxP sites flanking exons 3-6.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations