Allele/Variant

Tg(Nphs1-cre)10Mska

Species
Mus musculus
Symbol
Tg(Nphs1-cre)10Mska
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • Nephrin-Cre
Description
The cre recombinase cDNA was combined with a 5.5kb mouse Nphs1 promoter fragment and intron of the rabbit beta-globin gene. The construct was injected into fertilized eggs from (C57BL/6 x DBA/2) x C57BL/6N mice. Cre mRNA was detected in the kidney by Northern blot in five lines, and Cre protein was detected in podocytes by immunohistochemistry in four lines. Line 10 was established by backcrossing to C57BL/6 mice.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations