Allele/Variant

Scg3em1(IMPC)J

Species
Mus musculus
Symbol
Scg3em1(IMPC)J
Category
allele
Allele of gene
Scg3
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences TTGAGCCTAGTACGAAGCAT, GCTGGGCACTAGACATTCCC, ATAGGTTATGAAATGATGCG and GCAAGCACATTTTTACATCT, which resulted in a 406 bp deletion beginning at Chromosome 9 negative strand position 75,676,874 bp, TGAAATGATGCGTGGACTAG, and ending after GCTTGCCAGGGAATGTCTAG at 75,676,469 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000217477 (exon 5) and 263 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 136 and early truncation 1 amino acid later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations