Allele/Variant

Tg(Rho-GUCY2D*R838S)379Amd

Species
Mus musculus
Symbol
Tg(Rho-GUCY2D*R838S)379Amd
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • R838S RetGC1
Description
The transgene contains a 4.2-kbp mouse rod opsin gene fragment (harboring the promoter region and the 0.3-kb BGH polyadenylation signal-containing fragment) driving retinal expression of the human gene carrying a point mutation (C to A) coding for the amino acid substitution of serine for arginine at position 838 (R838S). Lines 377 (similar to 379), 379 (slow phenotype appearance) and 362 (faster phenotype appearance) were generated.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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