Allele/Variant

Tg(Myh6-Ptpn11*Q510E)#Krnz

Species
Mus musculus
Symbol
Tg(Myh6-Ptpn11*Q510E)#Krnz
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
None
Description
The murine alpha-myosin heavy chain promoter drives the expression of a Ptpn11 cDNA which contains the amino acid substitution of glutamate for glutamine at position 510 (Q510E). Q510E is a dominant-negative loss-of-function mutation. The pound symbol (#) is used when line is not specified and/or lines are pooled.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

No data available

Disease Associations

No data available