Allele/Variant

Tg(Ckm-Sgcg)4Mcn

Species
Mus musculus
Symbol
Tg(Ckm-Sgcg)4Mcn
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • MCKgsg line 4
Description
The full-length murine gamma-sarcoglycan cDNA is under the control of muscle-specific creatine kinase promoter followed by bovine growth hormone termination and polyadenylation signals. Four lines were generated (1-4). Line 4 carries approximately 36 copies relative to the endogenous gene and is a high expressing line.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal gait
MGI
abnormal skeletal muscle morphology
MGI
centrally nucleated skeletal muscle fibers
MGI
decreased body size
MGI
decreased locomotor activity
MGI
decreased skeletal muscle mass
MGI
dystrophic muscle
MGI
increased variability of skeletal muscle fiber size
MGI
premature death
MGI
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Disease Associations