Allele/Variant

Scrn3em1(IMPC)J

Species
Mus musculus
Symbol
Scrn3em1(IMPC)J
Category
allele
Allele of gene
Scrn3
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences TAGTGATCGCCTCTTCCCAA, GGAAGAGGCGATCACTATGA, CACTAATTAGTCCAAGCGCA and TTTCCCACTGTAGATGATGT, which resulted in a 344 bp deletion beginning at Chromosome 2 negative strand position 73,318,471 bp and ending after 73,318,128 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001271539 (exon 3) and 162 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 53 and early truncation 3 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
cataractMGI
Showing 1 - 1 of 1 rows
per page

Disease Associations