Version: 8.0.0
Date: Tue Jan 28 2025
Camsap3tm1.1Ltm
MGI:5912533
Allele of Camsap3
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Camsap3tm1.1Ltm

Species
Mus musculus
Symbol
Camsap3tm1.1Ltm
Category
allele
Allele of gene
Camsap3
Transgenic Constructs
None
Synonyms
  • Camsap3dc
Description
A loxP site and FRT-flanked neo cassette were inserted in intron 13 and a loxP site was inserted in intron 17 via homologous recombination. Cre-mediated recombination removed the neo cassette and exons 14-17. RT-PCR confirmed the expression of a truncated transcript lacking the CKK domain essential for the binding to microtubules. In polarized epithelial cells the mutant protien fails to collect in the apical cortical area of cell-cell junctions.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page