Slc9a8^{tm1c(KOMP)Wtsi}

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Species

Mus musculus

Symbol

Slc9a8^{tm1c(KOMP)Wtsi}

Category

allele

Allele of gene

Slc9a8

Transgenic Constructs

None

Synonyms

• Nhe8^lox

Description

The L1L2_gt1 cassette was inserted at position 167282591 of Chromosome 2 upstream of the critical exon 4 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of exon 4 at position 167283331. Exon 4 is thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele to remove the lacZ sequence and neo selection cassette, leaving loxP sites flanking exon 4.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations