Pias3^tm1.2Asw

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Species

Mus musculus

Symbol

Pias3^tm1.2Asw

Category

allele

Allele of gene

Pias3

Transgenic Constructs

None

Synonyms

None

Description

A loxP site was inserted into intron 1 and a second loxP site and an FRT site flanked neomycin resistance gene cassette into intron 5. The neo cassette was removed through subsequent flp-mediated recombination. Exons 2-5 were deleted through cre-mediated recombination by crossing these mice with mice carrying the Tg(rx3-icre)1Mjam allele. That allele shows leaky expression in the oocytes, thus creating some non-conditional null mouse lines i this crossing.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations