Allele/Variant

Kcnk16em1(IMPC)J

Species
Mus musculus
Symbol
Kcnk16em1(IMPC)J
Category
allele
Allele of gene
Kcnk16
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GGGAATATGCTTTATCCCGG, AATGGACCCCAAGCTCAGCA, CTAAGACACTAAGTGGCCAG and CTTAGGCCCTGGCTTCCCAC, which resulted in a 400 bp deletion beginning at Chromosome 14 positive strand position 20,265,075 bp and ending after 20,265,474 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000239215 (exon 2) and 285 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 72 and early truncation 19 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations