Allele/Variant

Dtx3em1(IMPC)J

Species
Mus musculus
Symbol
Dtx3em1(IMPC)J
Category
allele
Allele of gene
Dtx3
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences TTACCCCCTGGACGCCAGGC, TCTTCCCGCCTGGCGTCCAG, GTCGTTCGTCCTGTCCAGAA and CTGTCCAGAATGGCAGCCTG, which resulted in a 736 bp deletion beginning at Chromosome 10 positive strand position 127,192,621 bp and ending after 127,193,356 bp (GRCm38/mm10). This mutation creates an internal deletion in ENSMUSE00000519601 (exon 4) and is predicted to cause a change of amino acid sequence after residue 1 and early truncation 32 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations