Allele/Variant

Pakapem1(IMPC)J

Species
Mus musculus
Symbol
Pakapem1(IMPC)J
Category
allele
Allele of gene
Pakap
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences CATGGCTTTCGGTATCTGCT, AGACAACAGATGACACCTTT, CGTGCTGCGACTTTTCCCTG and TCCTAAATAGATACTGGTGT, which resulted in a 292 bp deletion beginning at Chromosome 4 negative strand position 57,648,243 bp and ending after 57,647,952 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001288752 (exon 3) and 161 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 42 and early truncation 10 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations