Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Myh6-CRYAB*R120G)7302Ijb
MGI:6103872Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Myh6-CRYAB*R120G)7302Ijb

Species
Mus musculus
Symbol
Tg(Myh6-CRYAB*R120G)7302Ijb
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • hR120GCryAB High Tg
Description
The mouse alpha-myosin heavy chain promoter drives the expression of the human alphaB-crystallin with the missense R120G mutation. Two lines were established: 7302 and 7313. Total Cryab protein, both endogenous and transgene expression, is increased 6-fold in this line.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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