Hltf^tm1.1Hdin

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Species

Mus musculus

Symbol

Hltf^tm1.1Hdin

Category

allele

Allele of gene

Hltf

Transgenic Constructs

None

Synonyms

None

Description

The genomic sequence for the coding part of exon 1 plus exons 2-5 (coding for amino-acids 2-208) was replaced with a lacZ reporter gene cassette and a loxP site flanked neomycin resistance gene cassette. The neo cassette was removed through subsequent Cre-mediated recombination, leaving a combined reporter null allele. Northern blot and RT-PCR analysis confirmed the absence of endogenous transcripts from this allele.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations