Allele/Variant

Jak3m1J

Species
Mus musculus
Symbol
Jak3m1J
Category
allele
Allele of gene
Jak3
Transgenic Constructs
None
Synonyms
None
Description
This spontaneous G to A transition in exon 24 results in a missense mutation, changing codon 1081 from CGG, arginine, to CAG, glutamine. This occurred in a gene sequence already containing the A to C transversion in codon 1032 common in at least 27 inbred strains, which causes an amino acid change from serine to arginine.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations