ENU-induced T to A transversion at base pair 4,339,548 (v38) on chromosome 18, or base pair 13,865 in the NC_000084 GenBank genomic region. The mutation corresponds to residue 946 in the mRNA sequence NM_008713 within exon 5 of 8 total exons. The mutation results in a serine to arginine substitution at position 274 (S274R) in the protein.