H2-K1^d-em1Dvs

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Species

Mus musculus

Symbol

H2-K1^d-em1Dvs

Category

allele

Allele of gene

H2-K1

Transgenic Constructs

None

Synonyms

• H2-K1^em1Dvs

Description

This single nucleotide (G) deletion within exon 2 was shown by flow cytometry to cause a null allele. it was generated by injection of Cas9 and guide sequences GTACATCTCTGTCGGCTATG targeting H2-D1^b and ATAATCCGAGATTTGAGCCG targeting H2-K1^d into NOD/ShiLtDvs embryos, which resulted in this point deletion and the intragenic deletions of H2-D1^em5Dvs.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations