Zfand2b^tm1Otin

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Species

Mus musculus

Symbol

Zfand2b^tm1Otin

Category

allele

Allele of gene

Zfand2b

Transgenic Constructs

None

Synonyms

• Zfand2b^-

Description

A FRT-flanked trapping element consisting of a splice acceptor sequence followed by a neomycin resistance gene and a loxP site were inserted into introns 1-2. A second loxP site was inserted into introns 8-9 so that exons 2-8 were floxed. qRT-PCR analysis demonstrated the loss of mRNA expression in liver, muscle and bone marrow tissue from homozygous mutant mice. Western blot analysis confirmed absence of encoded protein.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations