Spata16^em1Osb

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Species

Mus musculus

Symbol

Spata16^em1Osb

Category

allele

Allele of gene

Spata16

Transgenic Constructs

None

Synonyms

• Spata16^{em1(R284Q)Osb)}
• Spata16^em1Maik

Show All 3

Description

A point mutation (G to A) was introduced in codon 851 of exon 4, predicted to result in a R284Q alteration in the encoded protein. This mouse mutation corresponds to the single amino acid substitution (c.848G>A or R283Q) identified in infertile globozoospermic patients. RT-PCR analysis indicated that the point mutation caused no splicing abnormality.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations