Hmces^em2Dfel

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Species

Mus musculus

Symbol

Hmces^em2Dfel

Category

allele

Allele of gene

Hmces

Transgenic Constructs

None

Synonyms

• Srap1 delta71

Description

Cas9 mRNA and single-guide RNA (sgRNA) targeting exon 2 was microinjected into the cytoplasm of zygote-stage embryos to induce deletions. Injected embryos were implanted in CD-1 foster mice and pups screened for deletions. Two lines were generated. This allele has a 71 bp deletion encompassing the translation initiation codon and catalytic invariant Cys2 codon.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations