Allele/Variant

Spred3em1(IMPC)Tcp

Species
Mus musculus
Symbol
Spred3em1(IMPC)Tcp
Category
allele
Allele of gene
Spred3
Transgenic Constructs
None
Synonyms
None
Description
This allele from project TCPR0439 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and four guide RNAs with spacer sequences of GTGGGTGTACTGGTGGCTTG and GTTAGGGAGAACGCTCAAAC targeting the 5' side and TATTGAGCTTGAGGTTGGCC and TACTGGTGTGTCACCAGGTG targeting the 3' side of a critical region. This resulted in a 1928 bp deletion & 12bp insTAAAAGGGATAA of Chr7 from 29166134 to 29168061. (GRCm38).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
decreased prepulse inhibitionMGI
enlarged lymph nodesMGI
enlarged ovaryMGI
increased circulating creatinine levelMGI
increased freezing behaviorMGI
microphthalmiaMGI
small kidneyMGI
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Disease Associations

No data available