Allele/Variant

Edc3em1(IMPC)Tcp

Species
Mus musculus
Symbol
Edc3em1(IMPC)Tcp
Category
allele
Allele of gene
Edc3
Transgenic Constructs
None
Synonyms
None
Description
This allele from project TCPR0903 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of CTATCACTCTACCTTCCCGA and TACCTATTGAAGGAGCGAAT targeting the 5' side and TACAGGAGTTGTGCCGACGA and CCCCGTTACATGAGTAATGA targeting the 3' side of exon ENSMUSE00000751233 and ENSMUSE00000257623. This resulted in a 904-bp deletion of Chr9 from 57715453 to 57716356 with a 4-bp insertion AAGG (GRCm38).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal eye morphology
MGI
abnormal kidney morphology
MGI
abnormal skin morphology
MGI
abnormal testis morphology
MGI
decreased prepulse inhibitionMGI
enlarged kidney
MGI
enlarged lymph nodesMGI
enlarged urinary bladder
MGI
increased circulating alkaline phosphatase level
MGI
increased mean platelet volumeMGI
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Disease Associations

No data available