Katnal2^m1Anu

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Species

Mus musculus

Symbol

Katnal2^m1Anu

Category

allele

Allele of gene

Katnal2

Transgenic Constructs

None

Synonyms

• Katnal2^Y86C

Description

The molecular lesion is an A-to-G substitution in codon 86 within exon3, resulting in the substitution of tyrosine (TAC) to cysteine (TGC) in the encoded protein. qPCR analysis of mRNA transcript levels in whole testis homogenates revealed no difference between homozygous mutant mice and wild-type controls. However, Western blot analysis of the 46 kDa isoform in whole testis homogenates revealed that protein expression is reduced to 41% of wild-type levels.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations