Allele/Variant

Gas2tm1(GFP/cre/ERT2)Pzg

Species
Mus musculus
Symbol
Gas2tm1(GFP/cre/ERT2)Pzg
Category
allele
Allele of gene
Gas2
Transgenic Constructs
Synonyms
None
Description
A GFP-Cre/ERT2 cassette and FRT-flanked Kanamycin/neomycin selection cassette were inserted into the first coding exon. RT-PCR and Western blot analysis confirmed absence of mRNA and protein, respectively, in homozygotes.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal basal lamina morphologyMGI
abnormal granulosa cell morphologyMGI
abnormal ovarian folliculogenesisMGI
abnormal ovary developmentMGI
abnormal ovary morphologyMGI
decreased corpora lutea numberMGI
decreased litter sizeMGI
decreased ovulation rateMGI
decreased tertiary ovarian follicle numberMGI
polyovular ovarian follicleMGI
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Disease Associations

No data available