Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Fabp4-LMNA*R482Q)#Hjw
MGI:6188858Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Fabp4-LMNA*R482Q)#Hjw

Species
Mus musculus
Symbol
Tg(Fabp4-LMNA*R482Q)#Hjw
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
None
Description
This transgene consists of the adipose-specific 5.4-kb fatty acid binding protein 4 promoter, cDNA encoding a FLAG epitope tag fused in frame to the full-length human prelamin A containing a substitution of a basic arginine with a neutral glutamine at amino acid 482 (R482Q), an SV40 splice site and a polyadenylation site. FLAG-tagged proteins are selectively expressed in extracts of adipose tissue but not liver.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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