Version: 8.0.0
Date: Tue Jan 28 2025
Gt(ROSA)26Sortm2(CAG-Lin28b,-luc)Jhsc
MGI:6196138
Allele of Gt(ROSA)26Sor
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Gt(ROSA)26Sortm2(CAG-Lin28b,-luc)Jhsc

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm2(CAG-Lin28b,-luc)Jhsc
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
Synonyms
None
Description
Recombinase-mediated cassette exchange (RMCE) replaced the selection cassette in Gt(ROSA)26Sortm1(CAG-flpe)Arte with a 5' deleted neomycin resistance cassette, the CAG promoter, loxP flanked strong transcriptional termination site (LSL), the mouse Lin28b gene, IRES, and the firefly luciferase gene. Cre-mediated recombination can be utilized to remove the STOP cassette and get expression of the Lin28b gene.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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