Version: 8.0.0
Date: Tue Jan 28 2025
Rbp4tm2Zhel
MGI:6196354
Allele of Rbp4
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Rbp4tm2Zhel

Species
Mus musculus
Symbol
Rbp4tm2Zhel
Category
allele
Allele of gene
Rbp4
Transgenic Constructs
None
Synonyms
  • Rbp4-
Description
A null allele was created by replacing the ATG start site within exon 2 with a PGK-neo cassette flanked by lox71 and loxP sites. Besides disrupting the gene, the cassette also serves as an acceptor in recombination mediated cassette exchange (RMCE). RT-PCR confirmed absence of mRNA in the brain, lung, liver, and kidney. Northern blots of liver RNA and Western blots of serum confirmed absence of mRNA and protein, respectively.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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