Ankrd16^{rs251476964-A}

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Species

Mus musculus

Symbol

Ankrd16^{rs251476964-A}

Category

allele

Allele of gene

Ankrd16

Transgenic Constructs

None

Synonyms

• Msti^B6

Description

The A SNP at this location results in an alternate splice site and the inclusion of a 138 bp cryptic exon (5'). QRT-PCR confirmed reduced transcript levels, likely due to nonsense mediated decay. Western blot analysis confirmed reduced protein levels in heterozygotes. This variant was identified in C57BL/6J and is present in multiple strains (determined by SNP analysis and confirmed by the lack of modifier of Aars^sti phenotype activity in MOLF/Ei, DBA/2J, BALB/cJ and C3H/HeJ crosses).

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations