ENU-induced A to G transition at base pair 52,139,264 (v38) on chromosome 1, or base pair 19,827 in the GenBank genomic region NC_000067. The mutation corresponds to residue 1,155 in the mRNA sequence NM_001205313 within exon 10 of 25 total exons.The mutation results in a lysine to glutamic acid substitution at amino acid 286 (K286E) in the STAT1 protein.