ENU-induced G to A transition at base pair 117,284,929 (v38) on chromosome 2, or base pair 57,949 in the GenBank genomic region NC_000068 encoding Rasgrp1. The mutation corresponds to residue 2,345 in the mRNA sequence NM_011246 within exon 16 of 17 total exons. The mutation results in substitution of tryptophan 726 for a premature stop codon (W726*).