Version: 8.0.0
Date: Tue Jan 28 2025
Albem1(dre/ERT2)Bzsh
MGI:6202045
Allele of Alb
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Albem1(dre/ERT2)Bzsh

Species
Mus musculus
Symbol
Albem1(dre/ERT2)Bzsh
Category
allele
Allele of gene
Alb
Transgenic Constructs
Synonyms
  • Alb-DreER
Description
The line was generated by inserting a cDNA encoding IRES-Dre recombinase fused with a mutant form of estrogen receptor hormon-binding domaine C (ERT2) into in-frame with the translational termination codon of the last coding exon of Alb by homologous recombination using the CRISPR/Cas9 technology. This knock-in strategy leads to simultaneous expression of DreER and endogenous albumin.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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