Allele/Variant

Dennd6aem1(IMPC)J

Species
Mus musculus
Symbol
Dennd6aem1(IMPC)J
Category
allele
Allele of gene
Dennd6a
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGTATGCCGAAAATTCTAGT and TACATGACGAGTAGCCAGCA, which resulted in a 352 bp deletion beginning at Chromosome 14 position 26,592,173 bp and ending after 26,592,524 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000355312, and ENSMUSE00000398626 (exons 2 and 3) and 270 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 77 and early truncation 35 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations