Vps26c^em1(IMPC)J

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Species

Mus musculus

Symbol

Vps26c^em1(IMPC)J

Category

allele

Allele of gene

Vps26c

Transgenic Constructs

None

Synonyms

None

Description

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGGTAAGAAGCTGCGTAAGT and GTACACATATTAGGGACAAA, which resulted in a 1215 bp deletion beginning at Chromosome 16 position 94,501,242 bp and ending after 94,502,456 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000131739, ENSMUSE00000131736 (exons 5,6) and 911 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 169 and early truncation 21 amino acids later.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations