Slain2^em1(IMPC)J

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Species

Mus musculus

Symbol

Slain2^em1(IMPC)J

Category

allele

Allele of gene

Slain2

Transgenic Constructs

None

Synonyms

None

Description

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AGTATAGGACTATAAAGTAG and TTGAGTGTGTATATTTAGGC, which resulted in a 287 bp deletion beginning at Chromosome 5 position 72,941,237 bp and ending after 72,941,523 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001058225 (exon 2) and 138 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 129 and early truncation 9 amino acids later.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations