Allele/Variant

Klhl40em1(IMPC)J

Species
Mus musculus
Symbol
Klhl40em1(IMPC)J
Category
allele
Allele of gene
Klhl40
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGTTAGGCAGATAAAAAGGG and GGACCACAGCAGCAACCAGG, which resulted in a 471 bp deletion beginning at Chromosome 9 position 121,779,701 bp and ending after 121,780,171 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000633486 (exon 2) and 310 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 384 and early truncation 5 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations