Sema4c^m1Btlr

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Species

Mus musculus

Symbol

Sema4c^m1Btlr

Category

allele

Allele of gene

Sema4c

Transgenic Constructs

None

Synonyms

• swirl

Description

ENU-induced G to T transversion at base pair 36,550,311 (v38) on chromosome 1, or base pair 8,071 in the GenBank genomic region NC_000067 encoding Sema4c. The mutation corresponds to residue 2,251 in the NM_001304330 mRNA sequence in exon 16 of 16 total exons, to residue 2,136 in the NM_001126047 mRNA sequence in exon 15 of 15 total exons, and to residue 1,971 in the NM_001304329 mRNA sequence in exon 15 of 15 total exons. The mutation results in a cysteine (C) to phenylalanine (F) substitution at position 578 (C578F) in all isoforms of the SEMA4C protein.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations