Allele/Variant

Rsf1tm1c(EUCOMM)Wtsi

Species
Mus musculus
Symbol
Rsf1tm1c(EUCOMM)Wtsi
Category
allele
Allele of gene
Rsf1
Transgenic Constructs
None
Synonyms
  • Rsf1LoxP
Description
The L1L2_gt0 cassette was inserted at position 97288085 of Chromosome 7 upstream of the critical exon 4 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon 4 at position 97288972. The critical exon 4 is thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele to remove the lacZ sequence and neo selection cassette, leaving loxP sites flanking the critical exon 4. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations