Allele/Variant

Iqchem1(IMPC)J

Species
Mus musculus
Symbol
Iqchem1(IMPC)J
Category
allele
Allele of gene
Iqch
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTAAACGCCGTTTCGAGCGA and GTAATTGATGAAGTGTTAGT, which resulted in a 1108 bp deletion beginning at Chromosome 9 position 63,524,247 bp and ending after 63,525,354 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000324999 (exon 10) and 456 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 288, remove 188 amino acids, and return into frame for the stop codon.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations