Allele/Variant

Mroh2bem1(IMPC)J

Species
Mus musculus
Symbol
Mroh2bem1(IMPC)J
Category
allele
Allele of gene
Mroh2b
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AGTGGTTTCCTTCAGACCCA and GCTTTAATAGCTTAAAGTAT, which resulted in a 1100 bp deletion beginning at Chromosome 15 position 4,904,805 bp and ending after 4,905,904 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000124014 and ENSMUSE00000124016 (exons 5 and 6) and 846 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 116 and early truncation 5 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations