Allele/Variant

Brme1em1(IMPC)J

Species
Mus musculus
Symbol
Brme1em1(IMPC)J
Category
allele
Allele of gene
Brme1
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCAGGAAGTTCATAGCCACA and CCACCACTGCAACCCTTTCT, which resulted in a 531 bp deletion beginning at Chromosome 8 position 84,159,196 bp and ending after 84,159,726 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000267236 (exon 3) and 368 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 9 and early truncation 43 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations