Allele/Variant

Triobpem1(IMPC)J

Species
Mus musculus
Symbol
Triobpem1(IMPC)J
Category
allele
Allele of gene
Triobp
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CCTGCGCTAAGGAAGGGCTA and CATTACTGTTTCATAAGCCA, which resulted in a 223 bp deletion beginning at Chromosome 15 position 78,957,051 bp and ending after 78,957,273 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001213855 (exon 4) and 123 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 8 and early truncation 141 amino acids later. In addition, there is a single (G) bp insertion at the deletion site.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations