Arl5a^em1(IMPC)J

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Species

Mus musculus

Symbol

Arl5a^em1(IMPC)J

Category

allele

Allele of gene

Arl5a

Transgenic Constructs

None

Synonyms

None

Description

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GTTAACGTTGAGTCTCTGTA and TGGCCGTGTAGAATGAGAAG, which resulted in a 1020 bp deletion beginning at Chromosome 2 position 52,415,850 bp and ending after 52,416,869 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000264020 and ENSMUSE00000264010 (exons 2 and 3) and 811 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 15 and early truncation 17 amino acids later.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations