Allele/Variant

Tg(tetO-CHMP2B*)3Fbga

Species
Mus musculus
Symbol
Tg(tetO-CHMP2B*)3Fbga
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • CHMP2BIntron5
Description
The human CHMP2B cDNA containing a missense mutation in the splice acceptor site of exon 6, a mutation identified in human familial FTD, is under the control of the tetracycline promoter. The mutation results in a truncation at the carboxy terminus such that the microtubule interacting and trafficking motif is lost.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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